Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interrelationship of childhood trauma, neuroticism, and depressive phenotype.

Depression and anxiety - 1 Jan 2007

Moskvina Valentina, Farmer Anne, Swainson Victoria, O'Leary Joanna, Gunasinghe Cerise, Owen Mike, Craddock Nick, McGuffin Peter, Korszun Ania

Abstract excerpt

Both childhood trauma (CT) and genetic factors contribute to the pathophysiology of depression. We studied the relationship of CT to age of onset (AO) of depression, personality traits, and expression of symptom dimensions in 324 adults with recurrent unipolar depression. Subjects received structured psychiatric interviews and completed CT, depressive symptom, and personality rating questionnaires. Experience of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child Abuse
Share to Depressive Disorder

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to International Classification of Diseases

Share to Neurotic Disorders

Share to Observer Variation

Share to Personality Disorders

Share to Siblings

Share to Stress Disorders, Post-Traumatic

Source

Identifiers

PMID: 16900462
DOI: 10.1002/da.20216

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interrelationship of childhood trauma, neuroticism, and depressive phenotype.PMID 16900462Read ↗

Etiology of depression: genetic and environmental factors.Semantic proximity Read ↗

The association between trauma exposure, polygenic risk and individual depression symptoms.Semantic proximity Read ↗

Childhood trauma in mood disorders: Neurobiological mechanisms and implications for treatmentSemantic proximity Read ↗

Gene–Environment Interactions and Intermediate Phenotypes: Early Trauma and DepressionSemantic proximity Read ↗

Evidence that genes for depression impact on the pathway from trauma to psychotic-like symptoms by occasioning emotional dysregulation.Semantic proximity Read ↗

Interactions of childhood maltreatment and genetic variations in adult depression: A systematic review.Semantic proximity Read ↗

Early Life Trauma Predicts Affective Phenomenology and the Effects are Partly Mediated by Staging Coupled with Lowered Lipid-Associated Antioxidant DefencesSemantic proximity Read ↗

Genetics, epigenetics, and neurobiology of childhood-onset depression: an umbrella review.Semantic proximity Read ↗

Genome-by-Trauma Exposure Interactions in Adults With Depression in the UK Biobank.Semantic proximity Read ↗

Assessing the contributions of childhood maltreatment subtypes and depression case-control status on telomere length reveals a specific role of physical neglectSemantic proximity Read ↗

Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium.Semantic proximity Read ↗

Moderation of the association between childhood maltreatment and neuroticism by the corticotropin-releasing hormone receptor 1 gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.