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Article

Moderation of the association between childhood maltreatment and neuroticism by the corticotropin-releasing hormone receptor 1 gene.

Journal of child psychology and psychiatry, and allied disciplines - 1 Aug 2011

DeYoung Colin G, Cicchetti Dante, Rogosch Fred A

Abstract excerpt

BACKGROUND: Neuroticism is a personality trait reflecting the tendency to experience negative affect. It is a major risk for psychopathology, especially depression and anxiety disorders. Childhood maltreatment is another major risk factor for psychopathology and may influence personality. Maltreatment may interact with genotype to predict developmental outcomes. Variation in three polymorphisms of the CRHR1 gene...

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Source

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Identifiers

PMID: 21438878
DOI: 10.1111/j.1469-7610.2011.02404.x
PMCID: PMC3134545

Genes

CRHR1
TAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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