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Article

Etiology of depression: genetic and environmental factors.

The Psychiatric clinics of North America - 1 Mar 2012

Saveanu Radu V, Nemeroff Charles B

Abstract excerpt

In summary, depressed patients with a history of childhood trauma may have a distinct depression endophenotype characterized by a specific neurobiology and risk genotype that may be responsive to different treatment strategies than depressed patients without childhood adversity. Based on current findings, treatment strategies should be multimodal and include the following: 1. Psychotherapy that addresses a number...

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PMID: 22370490
DOI: 10.1016/j.psc.2011.12.001

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