Genetics, epigenetics, and neurobiology of childhood-onset depression: an umbrella review.

Abstract excerpt

Depression is a serious and persistent psychiatric disorder that commonly first manifests during childhood. Depression that starts in childhood is increasing in frequency, likely due both to evolutionary trends and to increased recognition of the disorder. In this umbrella review, we systematically searched the extant literature for genetic, epigenetic, and neurobiological factors that contribute to a childhood...

Topics

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• Age of Onset
• Child
• Depression
• Depressive Disorder
• Epigenesis, Genetic