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Article

Programmed Transcription of the var Gene Family, but Not of stevor , in Plasmodium falciparum Gametocytes

1 Aug 2006

Abstract excerpt

The var genes encode Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) proteins, a set of highly diverse surface-expressed proteins that mediate adhesion of erythrocytes infected with asexual blood-stage parasites to host endothelium. Switching among expressed PfEMP1 variants in the course of a blood-stage infection is a key component of antigenic variation, and thus immune evasion, by the parasite....

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PMID: 16896206
DOI: 10.1128/ec.00029-06

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