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Expression of Plasmodium falciparum erythrocyte membrane protein 1 in experimentally infected humans

27 Apr 2005

Abstract excerpt

BACKGROUND: Parasites causing severe malaria in non-immune patients express a restricted subset of variant surface antigens (VSA), which are better recognized by immune sera than VSA expressed during non-severe disease in semi-immune individuals. The most prominent VSA are the var gene-encoded Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family, which is expressed on the surface of infected...

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PMID: 15857512
DOI: 10.1186/1475-2875-4-21

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