Article

Transcriptional plasticity of virulence genes provides malaria parasites with greater adaptive capacity for avoiding host immunity

2024-03-09

Abstract excerpt

Chronic, asymptomatic malaria infections contribute substantially to disease transmission and likely represent the most significant impediment preventing malaria elimination and eradication. Plasmodium falciparum parasites evade antibody recognition through transcriptional switching between members of the var gene family, which encodes the major virulence factor and surface antigen on infected red blood cells. T...

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Identifiers and source

Literature Corpus work: 4314eba2-4e64-59fc-962f-64f071465cfe
DOI: 10.1101/2024.03.08.584127

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