Article
Multiple var gene transcripts are expressed in Plasmodium falciparum infected erythrocytes selected for adhesion.
Molecular and biochemical parasitology - 1 May 2001
Noviyanti R, Brown G V, Wickham M E, Duffy M F, Cowman A F, Reeder J C
Abstract excerpt
Adherence of Plasmodium falciparum-infected erythrocytes to the post-capillary endothelium is an important characteristic of malaria infection. The adhesion is mediated predominantly by P. falciparum Erythrocyte Membrane Protein-1 (PfEMP1), a clonally variant protein expressed on the surface of infected red blood cells that appears to be a target of protective immunity. A multi-membered var gene family encodes...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
