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Article

A well‐conserved <i>Plasmodium falciparum var</i> gene shows an unusual stage‐specific transcript pattern

29 Apr 2003

Abstract excerpt

The var multicopy gene family encodes Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) variant antigens, which, through their ability to adhere to a variety of host receptors, are thought to be important virulence factors. The predominant expression of a single cytoadherent PfEMP1 type on an infected red blood cell, and the switching between different PfEMP1 types to evade host protective antibody...

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PMID: 12787360
DOI: 10.1046/j.1365-2958.2003.03505.x

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