Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High diversity and rapid changeover of expressed <i>var</i> genes during the acute phase of <i>Plasmodium falciparum</i> infections in human volunteers

25 Jul 2002

Abstract excerpt

Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) proteins expressed on the surface of P. falciparum-infected erythrocytes undergo antigenic variation by switching the gene expressed within a repertoire of approximately 50 var genes per haploid genome. The switching of PfEMP1 plays an important role in the survival and pathogenesis of the parasite. To understand how a parasite switches its var gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Malaria Research and Control
Share to Mosquito-borne diseases and control
Share to Trypanosoma species research and implications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12142467
DOI: 10.1073/pnas.162349899

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High diversity and rapid changeover of expressed <i>var</i> genes during the acute phase of <i>Plasmodium falciparum</i> infections in human volunteersPMID 12142467Read ↗

Mosquito Passage Dramatically Changes var Gene Expression in Controlled Human Plasmodium falciparum InfectionsSemantic proximity Read ↗

Rapid turnover of Plasmodium falciparum var gene transcripts and genotypes during natural non-symptomatic infections.Semantic proximity Read ↗

Highly co-ordinated var gene expression and switching in clinical Plasmodium falciparum isolates from non-immune malaria patients.Semantic proximity Read ↗

Diverse and weakly immunogenic<i>var</i>gene expression facilitates malaria infectionSemantic proximity Read ↗

<i>Plasmodium falciparum</i> Associated with Severe Childhood Malaria Preferentially Expresses PfEMP1 Encoded by Group A <i>var</i> GenesSemantic proximity Read ↗

Differential Changes inPlasmodium falciparum varTranscription during Adaptation to CultureSemantic proximity Read ↗

Repurposing of Plasmodium falciparum var genes beyond the blood stageSemantic proximity Read ↗

Antigenic variation in Plasmodium falciparum malaria involves a highly structured switching pattern.Semantic proximity Read ↗

Expression patterns of <i>Plasmodium falcip</i> arum clonally variant genes at the onset of a blood infection in non-immune humansSemantic proximity Read ↗

Antigenic Variation in<i>Plasmodium falciparum</i>Semantic proximity Read ↗

Expression Patterns of Plasmodium falciparum Clonally Variant Genes at the Onset of a Blood Infection in Malaria-Naive Humans.Semantic proximity Read ↗

Antigenic Variation in <i>Plasmodium falciparum</i> : Gene Organization and Regulation of the <i>var</i> Multigene FamilySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.