Article
Organization and post-transcriptional processing of focal adhesion kinase gene.
BMC genomics - 4 Aug 2006
Corsi Jean-Marc, Rouer Evelyne, Girault Jean-Antoine, Enslen Hervé
Abstract excerpt
BACKGROUND: Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase critical for processes ranging from embryo development to cancer progression. Although isoforms with specific molecular and functional properties have been characterized in rodents and chicken, the organization of FAK gene throughout phylogeny and its potential to generate multiple isoforms are not well understood. Here, we study the...
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