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Article

Somatic Mutations and Splicing Variants of Focal Adhesion Kinase in Non-Small Cell Lung Cancer.

Journal of the National Cancer Institute - 1 Feb 2018

Zhou Bo, Wang Gui-Zhen, Wen Zhe-Sheng, Zhou Yong-Chun, Huang Yun-Chao, Chen Ying, Zhou Guang-Biao

Abstract excerpt

Background: Overexpression of focal adhesion kinase (FAK) has been reported in lung cancer, but the somatic mutations and alternative splicing variants of this nonreceptor tyrosine kinase remain to be investigated. Methods: FAK in 91 lung cancer patients was sequenced using genomic DNA and cDNA samples of tumor and paired normal lung tissues as templates, and the RNA-seq data of The Cancer Genome Atlas (TCGA)...

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PMID: 29087503
DOI: 10.1093/jnci/djx157

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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