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Article

Functional analysis of Survivin in spindle assembly in Xenopus egg extracts.

Journal of cellular biochemistry - 1 Jan 2007

Canovas Pedro M, Guadagno Thomas M

Abstract excerpt

Survivin is a member of the inhibitor of apoptosis (IAP) protein family that serves critical roles in mitosis and cytokinesis. Many studies have suggested Survivin's involvement in spindle regulation, but direct biochemical evidence for this has been lacking. Using the cell-free system of Xenopus...

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PMID: 16888809
DOI: 10.1002/jcb.21065

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16888809-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Functional analysis of Survivin in spindle assembly in Xenopus egg extracts.PMID 16888809Read ↗

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Deconstructing Survivin: comprehensive genetic analysis of Survivin function by conditional knockout in a vertebrate cell line.Semantic proximity Read ↗

Cell division and cell survival in the absence of survivinSemantic proximity Read ↗

The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation.Semantic proximity Read ↗

INCENP is required for proper targeting of Survivin to the centromeres and the anaphase spindle during mitosis.Semantic proximity Read ↗

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