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Article

Cell division and cell survival in the absence of survivin

11 Oct 2004

Abstract excerpt

The survivin protein contains structural features of the inhibitor of apoptosis protein family. Previous studies have suggested that survivin is essential for cell survival because it counteracts an otherwise constitutive propensity to apoptosis during mitosis. In addition, survivin appears to be a component of the chromosomal passenger protein complex that participates in multiple facets of cell division. Here...

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Identifiers

PMID: 15477601
DOI: 10.1073/pnas.0406665101

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Cell division and cell survival in the absence of survivinPMID 15477601Read ↗

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Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype.Semantic proximity Read ↗

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Survivin mutant (Surv-DD70, 71AA) disrupts the interaction of Survivin with Aurora B and causes multinucleation in HeLa cells.Semantic proximity Read ↗

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