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Article

Knockdown of B-Raf impairs spindle formation and the mitotic checkpoint in human somatic cells.

Cell cycle (Georgetown, Tex.) - 15 Sept 2008

Borysova M K, Cui Y, Snyder M, Guadagno T M

Abstract excerpt

It is well established that B-Raf signaling through the MAP kinase (ERK) pathways plays a prominent role in regulating cell proliferation but how it does this is not completely understood. Here, we show that B-Raf serves a physiological role during mitosis in human somatic cells. Knockdown of B-R...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins c-raf

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Source

Identifiers

PMID: 18787396
DOI: 10.4161/cc.7.18.6678

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18787396-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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