Article
Human survivin is a kinetochore-associated passenger protein.
The Journal of cell biology - 25 Dec 2000
Skoufias D A, Mollinari C, Lacroix F B, Margolis R L
Abstract excerpt
Survivin, a dimeric baculovirus inhibitor of apoptosis repeat (BIR) motif protein that is principally expressed in G2 and mitosis, has been associated with protection against apoptosis of cells that exit mitosis aberrantly. Mammalian survivin has been reported to associate with centrosomes and with the mitotic spindle. We have expressed a human hemagglutinin-tagged survivin plasmid to determine its localization,...
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