Article
Identification of a putative nuclear localization sequence within ANG II AT(1A) receptor associated with nuclear activation.
American journal of physiology. Cell physiology - 1 Apr 2007
Morinelli Thomas A, Raymond John R, Baldys Aleksander, Yang Qing, Lee Mi-Hye, Luttrell Louis, Ullian Michael E
Abstract excerpt
Angiotensin II (ANG II) type 1 (AT(1)) receptors, similar to other G protein-coupled receptors, undergo desensitization and internalization, and potentially nuclear localization, subsequent to agonist interaction. Evidence suggests that the carboxy-terminal tail may be involved in receptor nuclear localization. In the present study, we examined the carboxy-terminal tail of the receptor for specific regions...
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