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Article

A genetic study of the suppressors of the Engrailed-1 cerebellar phenotype.

Brain research - 6 Apr 2007

Murcia Crystal L, Gulden Forrest O, Cherosky Natalie A, Herrup Karl

Abstract excerpt

The mouse Engrailed genes, En1 and En2, play an important role in the development of the cerebellum from its inception at the mid/hindbrain boundary in early embryonic development through cell type specification events and beyond. In the absence of En1, the cerebellum and caudal midbrain fail to develop normally--a phenotype that we have previously reported to be strain dependent. On the 129/S1 strain background,...

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Identifiers

PMID: 16884697
DOI: 10.1016/j.brainres.2006.06.076

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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