Article
Engrailed homeobox genes regulate establishment of the cerebellar afferent circuit map.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 28 Jul 2010
Sillitoe Roy V, Vogel Michael W, Joyner Alexandra L
Abstract excerpt
The spatial organization of the cerebellar afferent map has remarkable correspondence to two aspects of intrinsic patterning within the cerebellum embodied by a series of lobules and Purkinje cell (PC)-striped gene expression. Using male and female mice, we tested whether the Engrailed (En) homeobox genes are a common genetic substrate regulating all three systems, since they are expressed in spatially restricted...
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