Article
Multiple developmental defects in Engrailed-1 mutant mice: an early mid-hindbrain deletion and patterning defects in forelimbs and sternum.
Development (Cambridge, England) - 1 Jul 1994
Wurst W, Auerbach A B, Joyner A L
Abstract excerpt
During mouse development, the homeobox-containing gene En-1 is specifically expressed across the mid-hindbrain junction, the ventral ectoderm of the limb buds, and in regions of the hindbrain, spinal cord, somites and somite-derived tissues. To address the function of En-1 during embryogenesis, w...
Topics
- Animals
- Base Sequence
- Central Nervous System
- Forelimb
- Homeodomain Proteins
- Mice
- Mice, Mutant Strains
- Molecular Sequence Data
- Morphogenesis
- Phenotype
- Polymerase Chain Reaction
- Rhombencephalon
- Sternum