Article
In vivo commitment to yeast cotranscriptional splicing is sensitive to transcription elongation mutants.
Genes & development - 1 Aug 2006
Lacadie Scott A, Tardiff Daniel F, Kadener Sebastian, Rosbash Michael
Abstract excerpt
Spliceosome assembly in the budding yeast Saccharomyces cerevisiae was recently shown to occur at the site of transcription. However, evidence for cotranscriptional splicing as well as for coupling between transcription and splicing is still lacking. Using modifications of a previously published chromatin immunoprecipitation (ChIP) assay, we show that cotranscriptional splicing occurs approximately 1 kb after...
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