Article
GSTM1 and GSTP1 gene variants and the effect of air pollutants on lung function measures in South African children.
American journal of industrial medicine - 1 Dec 2012
Reddy Poovendhree, Naidoo Rajen N, Robins Thomas G, Mentz Graciela, Li Huiling, London Stephanie J, Batterman Stuart
Abstract excerpt
BACKGROUND: Several genes are associated with an increased susceptibility to asthma, which may be exacerbated by ambient air pollution. These genes include GSTM1 (glutathione-S-transferase M1 gene) and GSTP1 (glutathione-S-transferase P1 gene), which may modulate the response to epithelial oxidative changes caused by air pollutant exposure. This study evaluated fluctuations in the forced expiratory volume in one...
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