Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multidrug resistance phenotype associated with selection of an aminopterin resistant dog kidney cell line.

Pharmacogenetics - 1 Dec 1991

Turker M S, Duffin K Z, Smith A C, Martin G M, Martin A W, DiMartino D L, Kersey D S

Abstract excerpt

A determination of the mechanisms of drug resistance in tumour cells is important for developing strategies to combat such resistance in persons receiving chemotherapy. This report describes a combined cellular, biochemical, and molecular analysis of a dog kidney cell line selected for resistance...

Topics

ATP Binding Cassette Transporter, Subfamily B, Member 1
Aminopterin
Animals
Cell Line
Colchicine
Dogs
Drug Resistance
Immunohistochemistry
Kidney
Membrane Glycoproteins
Phenotype
RNA, Messenger

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tetrahydrofolate Dehydrogenase

Source

Identifiers

PMID: 1688246
DOI: 10.1097/00008571-199112000-00005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1688246-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multidrug resistance phenotype associated with selection of an aminopterin resistant dog kidney cell line.PMID 1688246Read ↗

Multidrug-resistant phenotype of disease-oriented panels of human tumor cell lines used for anticancer drug screening.Semantic proximity Read ↗

[Multiple drug resistance and differentiation in the population of transformed dog kidney cells MDCK].Semantic proximity Read ↗

A phenotype conferring selective resistance to lipophilic antifolates in Chinese hamster ovary cells.Semantic proximity Read ↗

A mutation hot spot in the Bcrp1 (Abcg2) multidrug transporter in mouse cell lines selected for Doxorubicin resistance.Semantic proximity Read ↗

Expression of a human complementary DNA for the multidrug resistance gene in murine hematopoietic precursor cells with the use of retroviral gene transfer.Semantic proximity Read ↗

Molecular basis of preferential resistance to colchicine in multidrug-resistant human cells conferred by Gly-185----Val-185 substitution in P-glycoprotein.Semantic proximity Read ↗

Influence of chemosensitizers on resistance mechanisms in daunorubicin-resistant Ehrlich ascites tumour cells.Semantic proximity Read ↗

Characterization of auromomycin-resistant hamster cell mutants that display a multidrug resistance phenotype.Semantic proximity Read ↗

Pharmacological characterization of the murine and human orthologs of multidrug-resistance protein in transfected human embryonic kidney cells.Semantic proximity Read ↗

Development and characterization of two human tumor sublines expressing high-grade resistance to the cyanoguanidine CHS 828.Semantic proximity Read ↗

Multidrug resistance phenotype of human BRO melanoma cells transfected with a wild-type human mdr1 complementary DNA.Semantic proximity Read ↗

Isolation and characterization of Drosophila multidrug resistance gene homologs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.