[Multiple drug resistance and differentiation in the population of transformed dog kidney cells MDCK].

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Article

[Multiple drug resistance and differentiation in the population of transformed dog kidney cells MDCK].

Molekuliarnaia genetika, mikrobiologiia i virusologiia - 1 May 1990

Stavrovskaia A A, Stromskaia T P, Chernova O B, Dzhuraeva F Kh

Abstract excerpt

Sublines of the canine kidney epithelium cells (MDCK) resistant to various colchicine doses (0.3-5.0 mcg.ml-1) were obtained by multistep selection. The new lines were shown to possess multidrug-resistance (MDR) by means of Rhodamine 123 staining. The initial steps of resistance (2 mcg.ml-1, 300-...

Topics

8-Bromo Cyclic Adenosine Monophosphate
Animals
Cell Differentiation
Cell Line, Transformed
Colchicine
DNA
Dimethyl Sulfoxide
Dogs
Drug Resistance
Gene Expression
Kidney
Phenotype

Source

Open in PubMed

Identifiers

PMID: 2381439

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2381439-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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