Article
Association of mu-opioid receptor gene polymorphism (A118G) with variations in morphine consumption for analgesia after total knee arthroplasty.
Acta anaesthesiologica Scandinavica - 1 Aug 2006
Chou W-Y, Yang L-C, Lu H-F, Ko J-Y, Wang C-H, Lin S-H, Lee T-H, Concejero A, Hsu C-J
Abstract excerpt
BACKGROUND: Morphine consumption after a given surgical procedure can vary considerably. Studies show that single nucleotide polymorphism involving the nucleotide position 118 at exon 1 of the mu-opioid receptor gene (OPRM1) may play a role in mediating the effects of opioids. This study was performed to correlate the A118G polymorphism at OPRM1 with morphine consumption in patients undergoing total knee...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.