Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Combined catechol-O-methyltransferase and mu-opioid receptor gene polymorphisms affect morphine postoperative analgesia and central side effects.

Anesthesia and analgesia - 1 Feb 2011

Kolesnikov Yuri, Gabovits Boris, Levin Ariel, Voiko Edward, Veske Andres

Abstract excerpt

BACKGROUND: Previous studies have generated controversial results regarding the influence of the genetic variations of μ-opioid receptors on morphine analgesia and opioid-related side effects in the postoperative period. Few studies have been conducted attempting to assess the combined effects of variation within ≥2 genes in relation to morphine response. In this study, we investigated whether combined...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analgesics, Opioid
Share to Estonia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hysterectomy

Share to Morphine

Share to Pain, Postoperative

Share to Pain Threshold

Share to Prostatectomy

Share to Receptors, Opioid, mu

Source

Identifiers

PMID: 21127283
DOI: 10.1213/ANE.0b013e318202cc8d

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Combined catechol-O-methyltransferase and mu-opioid receptor gene polymorphisms affect morphine postoperative analgesia and central side effects.PMID 21127283Read ↗

The Effect of Genetic Variation on the Sensitivity to Opioid Analgesics in Patients With Postoperative Pain: An Updated Meta-analysis.Semantic proximity Read ↗

A118G single nucleotide polymorphism of human mu-opioid receptor gene influences pain perception and patient-controlled intravenous morphine consumption after intrathecal morphine for postcesarean analgesia.Semantic proximity Read ↗

The impact of genetic variation on sensitivity to opioid analgesics in patients with postoperative pain: a systematic review and meta-analysis.Semantic proximity Read ↗

OPRM1 A118G gene variant and postoperative opioid requirement: a systematic review and meta-analysis.Semantic proximity Read ↗

[Genetic polymorphism affects the clinical effects of opioids after surgery].Semantic proximity Read ↗

Polymorphism of the micro-opioid receptor gene (OPRM1 118A>G) affects fentanyl-induced analgesia during anesthesia and recovery.Semantic proximity Read ↗

Human opioid receptor A118G polymorphism affects intravenous patient-controlled analgesia morphine consumption after total abdominal hysterectomy.Semantic proximity Read ↗

A genetic association study of the functional A118G polymorphism of the human mu-opioid receptor gene in patients with acute and chronic pain.Semantic proximity Read ↗

Comparison of the Effects of OPRM1 A118G Polymorphism Using Different Opioids: A Prospective Study.Semantic proximity Read ↗

The μ-opioid receptor gene polymorphism 118A>G weakens the pharmacological action of buprenorphine.Semantic proximity Read ↗

Association of mu-opioid receptor gene polymorphism (A118G) with variations in morphine consumption for analgesia after total knee arthroplasty.Semantic proximity Read ↗

Association Between Human Pain-Related Genotypes and Variability in Opioid Analgesia: An Updated Review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.