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Article

OPRM1 A118G gene variant and postoperative opioid requirement: a systematic review and meta-analysis.

Anesthesiology - 1 Oct 2014

Hwang In Cheol, Park Ji-Young, Myung Seung-Kwon, Ahn Hong Yup, Fukuda Ken-ichi, Liao Qin

Abstract excerpt

BACKGROUND: Although a number of studies have investigated the association of the OPRM1 A118G polymorphism with pain response, a consensus has not yet been reached. METHODS: The authors searched PubMed, EMBASE, and the Cochrane Library to identify gene-association studies that explored the impact of the OPRM1 A118G polymorphism on postoperative opioid requirements through July 2013. Two evaluators independently...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25102313
DOI: 10.1097/ALN.0000000000000405

Genes

OPRM1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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