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Article

Effects of dopamine receptor type 1 and Gs protein alpha subunit gene polymorphisms on blood pressure at rest and in response to stress.

American journal of hypertension - 1 Aug 2006

Lu Yanhui, Zhu Haidong, Wang Xiaoling, Snieder Harold, Huang Ying, Harshfield Gregory A, Treiber Frank A, Dong Yanbin

Abstract excerpt

BACKGROUND: Exaggerated blood pressure (BP) response to behavioral stress has been recognized as an independent predictor of increased BP levels in human subjects. The coupling of dopamine receptor type 1 (DRD1) with stimulatory G-proteins plays an important role in BP regulation. Therefore, we investigated whether the A-48G polymorphism of the DRD1 gene and the T393C polymorphism of the Gs protein alpha subunit...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to GTP-Binding Protein alpha Subunits, Gs

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Share to Receptors, Dopamine D1

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Source

Identifiers

PMID: 16876683
DOI: 10.1016/j.amjhyper.2006.01.006

Genes

DRD1
GNAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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