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Article

The G protein-coupled receptor kinase 4 gene affects blood pressure in young normotensive twins.

American journal of hypertension - 1 Jan 2006

Zhu Haidong, Lu Yanhui, Wang Xiaoling, Treiber Frank A, Harshfield Gregory A, Snieder Harold, Dong Yanbin

Abstract excerpt

BACKGROUND: G protein-coupled receptor kinase 4 (GRK4) is involved in activity of dopamine receptors in renal proximal tubules and thus mediates sodium reabsorption and blood pressure (BP) regulation. The present study evaluated the impact of the GRK4 gene variants on BP levels in normotensive ad...

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Source

Identifiers

PMID: 16461192
DOI: 10.1016/j.amjhyper.2005.07.007

Genes

GRK4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16461192-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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