Article
Human choline transporter gene variation is associated with corticolimbic reactivity and autonomic-cholinergic function.
Biological psychiatry - 15 Nov 2006
Neumann Serina A, Brown Sarah M, Ferrell Robert E, Flory Janine D, Manuck Stephen B, Hariri Ahmad R
Abstract excerpt
BACKGROUND: Our previous work has shown genetic variation in the human choline transporter gene (CHT1) to be associated with depressive symptoms and autonomic cardiac (cholinergic) dysregulation. Here, functional magnetic resonance imaging (fMRI) was used to examine the relation between a single nucleotide polymorphism (SNP) in CHT1 on regional brain reactivity relevant to autonomic (cholinergic) function....
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