5-HTTLPR and COMTval158met genotype gate amygdala reactivity and habituation.

doi:10.1016/j.biopsycho.2011.02.014

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Article

5-HTTLPR and COMTval158met genotype gate amygdala reactivity and habituation.

Biological psychology - 1 Apr 2011

Lonsdorf Tina B, Golkar Armita, Lindstöm Kara M, Fransson Peter, Schalling Martin, Ohman Arne, Ingvar Martin

Abstract excerpt

Amygdala reactivity is a heritable trait, potentiated in affective disorders and associated with both the 5-HTTLPR and the COMTval158met polymorphism. Fifty-four healthy volunteers selected a priori based on gender and 5-HTTLPR/rs25531 and COMTval158met genotypes performed a passive viewing task of angry facial expressions using fMRI. Amygdala reactivity and habituation were investigated using the a priori...

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PMID: 21356267
DOI: 10.1016/j.biopsycho.2011.02.014

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COMT

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