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Article

Effects of HTR1A C(-1019)G on amygdala reactivity and trait anxiety.

Archives of general psychiatry - 1 Jan 2009

Fakra Eric, Hyde Luke W, Gorka Adam, Fisher Patrick M, Muñoz Karen E, Kimak Mark, Halder Indrani, Ferrell Robert E, Manuck Stephen B, Hariri Ahmad R

Abstract excerpt

CONTEXT: Serotonin 1A (5-hydroxytryptamine 1A [5-HT(1A)]) autoreceptors mediate negative feedback inhibition of serotonergic neurons and play a critical role in regulating serotonin signaling involved in shaping the functional response of major forebrain targets, such as the amygdala, supporting complex behavioral processes. A common functional variation (C[-1019]G) in the human 5-HT(1A) gene (HTR1A) represents 1...

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Identifiers

PMID: 19124686
DOI: 10.1001/archpsyc.66.1.33
PMCID: PMC2736132

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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