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Article

Cohort- and time-specific associations of CTLA4 genotypes with HIV-1 disease progression.

AIDS (London, England) - 1 Aug 2006

Shao Wenshuo, Lazaryan Aleksandr, Dorak M Tevfik, Penman-Aguilar Ana, Wilson Craig M, Margolick Joseph B, Goedert James J, Prins Maria, Tang Jianming, Kaslow Richard A

Abstract excerpt

BACKGROUND: CTLA4 in the chromosome 2q33 region encodes cytotoxic T-lymphocyte (CTL) associated antigen 4, which downregulates CTL responses. We examined the relationships between common CTLA4 variants and several outcomes of HIV-1 infection in adults and adolescents. METHODS: We studied 765 HIV-1-infected persons: 558 Caucasian seroconverters from three cohorts (MACS, ACS, and DCG) and 207 infected adolescents...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16868438
DOI: 10.1097/01.aids.0000238403.08497.3f

Genes

CTLA4
CCR5
ICOS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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