Article
Host genetics and HIV-1 viral load set-point in African-Americans.
AIDS (London, England) - 27 Mar 2009
Shrestha Sadeep, Aissani Brahim, Song Wei, Wilson Craig M, Kaslow Richard A, Tang Jianming
Abstract excerpt
OBJECTIVE: In a recent genome-wide association study of HIV-1-infected individuals in the Euro-CHAVI cohort, viral load set-point was strongly associated with genotypes defined by two single nucleotide polymorphisms (SNPs) (rs9264942 and rs2395029) within the human major histocompatibility complex (MHC) region on chromosome 6. We attempted to confirm this finding in African-Americans and to address whether these...
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