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Article

Protective Effect of Interleukin‐4 −589T Polymorphism on Human Immunodeficiency Virus Type 1 Disease Progression: Relationship with Virus Load

15 Apr 2002

Abstract excerpt

The interleukin (IL)-4 -589T allele bears a single nucleotide polymorphism at position -589 upstream from the open-reading frame of the IL-4 gene. To determine the influence of this allele on human immunodeficiency virus (HIV) type 1 disease, disease progression and serum virus load were assessed by IL-4 genotype in 427 white patients with known seroconversion dates who were followed in the French SEROCO cohort...

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PMID: 11930331
DOI: 10.1086/339825

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