Article
The cytotoxic lymphocyte antigen 4 polymorphisms affect response to hepatitis C virus-specific therapy in HIV(+) patients with acute and chronic hepatitis C virus co-infection.
AIDS (London, England) - 24 Aug 2010
Nischalke Hans Dieter, Vogel Martin, Mauss Stefan, Baumgarten Axel, Lutz Thomas, Danta Marc, Naumann Uwe, Coenen Martin, Sauerbruch Tilman, Rockstroh Jürgen K, Spengler Ulrich, Nattermann Jacob
Abstract excerpt
OBJECTIVE: Cytotoxic lymphocyte antigen 4 (CTLA4), a co-receptor expressed on T lymphocytes, is involved in the regulation of T-cell functions. Here, we analyzed the potential impact of the CTLA4 polymorphisms on response to hepatitis C virus (HCV)-specific treatment in HIV(+) patients co-infecte...
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