Article
Neither an intronic CA repeat within the CD48 gene nor the HERV-K18 polymorphisms are associated with type 1 diabetes.
Tissue antigens - 1 Aug 2006
Ramos-Lopez E, Ghebru S, Van Autreve J, Aminkeng F, Herwig J, Seifried E, Seidl C, Van der Auwera B, Badenhoop K
Abstract excerpt
Type 1 diabetes is an autoimmune heterogeneous disease that is determined by environmental and genetic factors. A possible retroviral etiology has been inferred from the observation that human endogenous retrovirus (HERV)-K18 encoding a superantigen (SAg) has a polymorphism associated with this disease. Type 1 diabetes families from Germany and Belgium were genotyped for the novel HERV-8914 (303 families) and for...
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