Article
No association of polymorphisms in human endogenous retrovirus K18 and CD48 with schizophrenia.
Psychiatric genetics - 1 Jun 2012
Nyegaard Mette, Demontis Ditte, Thestrup Britta Boserup, Hedemand Anne, Sørensen Karina Meden, Hansen Thomas, Werge Thomas, Hougaard David Michael, Yolken Robert H, Mortensen Preben Bo, Mors Ole, Børglum Anders D
Abstract excerpt
The human endogenous retrovirus HERV-K18 is located within intron 1 of CD48 on chromosome 1q and is still active in the human genome. Genetic variation in HERV-K18 single-nucleotide polymorphisms (SNPs) has previously been associated with an increased risk of schizophrenia (SZ) and with type 2 diabetes (T2D) among individuals with SZ. Here, we present a replication study of association of two SNPs in HERV-K18 and...
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