Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interleukin 18 promoter polymorphisms are not strongly associated with type I diabetes in a UK population.

Genes and immunity - 1 Mar 2005

Martin R J L, Savage D A, Carson D J, Maxwell A P, Patterson C C

Abstract excerpt

Interleukin 18 (IL18) is a proinflammatory cytokine whose levels are increased in the subclinical stage of insulin-dependent (type I) diabetes mellitus. Previous case-control studies have reported associations between IL18 -607C>A and -137G>C promoter polymorphisms and type I diabetes. We perform...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Mellitus, Type 1
Share to Genetic Linkage
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-18

Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

Share to United Kingdom

Source

Identifiers

PMID: 15674367
DOI: 10.1038/sj.gene.6364161

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15674367-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interleukin 18 promoter polymorphisms are not strongly associated with type I diabetes in a UK population.PMID 15674367Read ↗

Analysis of polymorphisms of the interleukin-18 gene in type 1 diabetes and Hardy-Weinberg equilibrium testing.Semantic proximity Read ↗

Interleukin IL-18 gene promoter polymorphisms in adult patients with type 1 diabetes mellitus and latent autoimmune diabetes in adults.Semantic proximity Read ↗

Lack of association of interleukin-18 gene promoter -607 A/C polymorphism with susceptibility to autoimmune diseases: a meta-analysis.Semantic proximity Read ↗

Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes.Semantic proximity Read ↗

Interleukin-18 promoter -607 C/A and -137 G/C polymorphisms and susceptibility to type 1 diabetes: A meta-analysis.Semantic proximity Read ↗

Lack of association of IL-10 promoter gene variants with type 1 diabetes in a French population.Semantic proximity Read ↗

Interleukin 18 (IL18) gene promoter polymorphisms are associated with type 1 diabetes mellitus in Brazilian patients.Semantic proximity Read ↗

Association of IL-18 promoter polymorphisms with predisposition to Type 1 diabetes.Semantic proximity Read ↗

Genetic variability in the TNF-alpha promoter is not associated with type II diabetes mellitus (NIDDM).Semantic proximity Read ↗

Genetic variation in IL6 gene and type 2 diabetes: tagging-SNP haplotype analysis in large-scale case-control study and meta-analysis.Semantic proximity Read ↗

Lack of association between Interleukin-18 gene promoter polymorphisms and onset of Alzheimer's disease.Semantic proximity Read ↗

Variants of the interleukin-10 promoter gene are associated with obesity and insulin resistance but not type 2 diabetes in caucasian italian subjects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.