Article
Human endogenous retrovirus-K18 Env as a risk factor in multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Nov 2008
Tai A K, O'Reilly E J, Alroy K A, Simon K C, Munger K L, Huber B T, Ascherio A
Abstract excerpt
BackgroundThe human endogenous retrovirus (HERV)-K18 Env is an Epstein-Barr virus (EBV)-associated superantigen. Given the evidence for a role of EBV in the etiology of multiple sclerosis (MS), HERV-K18 Env is a plausible candidate for association with MS.ObjectiveTo assess whether variation in HERV-K18 Env is a risk factor for MS.MethodsWe developed a single nucleotide polymorphism-based genotyping method to...
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