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Transcribed <i>var</i> Genes Associated with Placental Malaria in MalawianWomen

22 Jul 2006

Abstract excerpt

Determining the diversity of PfEMP1 sequences expressed by Plasmodium falciparum-infected erythrocytes isolated from placentas is important for attempts to develop a pregnancy-specific malaria vaccine. The DBLgamma and var2csa DBL3x domains of PfEMP1 molecules are believed to mediate placental sequestration of infected erythrocytes, so the sequences encoding these domains were amplified from the cDNAs of...

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PMID: 16861676
DOI: 10.1128/iai.01978-05

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Transcribed <i>var</i> Genes Associated with Placental Malaria in MalawianWomenPMID 16861676Read ↗

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