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Article

Immunodominance and immunodomination: critical factors in developing effective CD8+ T-cell-based cancer vaccines.

Advances in cancer research - 1 Jan 2006

Chen Weisan, McCluskey James

Abstract excerpt

The focusing of cellular immunity toward one, or just a few, antigenic determinant, even during immune responses to complex microorganisms or antigens, is known as immunodominance. Although described in many systems, the mechanisms of determinant immunodominance are only just beginning to be appreciated, especially in relation to the interplay between T cells of differing specificities and the interactions...

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PMID: 16860659
DOI: 10.1016/S0065-230X(06)95006-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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