Article
Superdominance among immunodominant H-2Kb-restricted epitopes and reversal by dendritic cell-mediated antigen delivery.
Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 1998
Sandberg J K, Grufman P, Wolpert E Z, Franksson L, Chambers B J, Kärre K
Abstract excerpt
To examine possible interference patterns between immunodominant CTL Ags, we analyzed the response to mixtures of five well-characterized H-2Kb-restricted epitopes, each of which had earlier been described as immunodominant within its antigenic system. Clear patterns of dominance were observed be...
Topics
- Adjuvants, Immunologic
- Animals
- Clone Cells
- Cytotoxicity, Immunologic
- Dendritic Cells
- H-2 Antigens
- Immunity, Cellular
- Immunodominant Epitopes
- Injections, Subcutaneous
- Lymphocyte Count
- Mice
