Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential Epitope Positioning within the Germline Antibody Paratope Enhances Promiscuity in the Primary Immune Response

1 Apr 2006

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune Cell Function and Interaction
Share to Monoclonal and Polyclonal Antibodies Research
Share to T-cell and B-cell Immunology

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 16618601
DOI: 10.1016/j.immuni.2006.02.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential Epitope Positioning within the Germline Antibody Paratope Enhances Promiscuity in the Primary Immune ResponsePMID 16618601Read ↗

Structural Diversity of B-Cell Receptor Repertoires along the B-cell Differentiation Axis in Humans and MiceSemantic proximity Read ↗

Sagacious Epitope Selection for Vaccines, and Both Antibody-Based Therapeutics and Diagnostics: Tips From Virology and Oncology<strong> </strong>Semantic proximity Read ↗

Antigen binding by conformational selection in near-germline antibodiesSemantic proximity Read ↗

Exploration of Specificity in Germline Monoclonal Antibody Recognition of a Range of Natural and Synthetic EpitopesSemantic proximity Read ↗

Adjustable Locks and Flexible Keys: Plasticity of Epitope–Paratope Interactions in Germline AntibodiesSemantic proximity Read ↗

Systems-Scale Structural Modeling Reveals the Germline Architecture of ImmunodominanceSemantic proximity Read ↗

Immunogenicity of Therapeutic Antibodies: Mechanisms, Prediction, and Mitigation Strategies in the Era of Personalized BiologicsSemantic proximity Read ↗

Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination.Semantic proximity Read ↗

Germline-Dependent Antibody Paratope States and Pairing Specific VH-VL Interface DynamicsSemantic proximity Read ↗

A comparison of the binding sites of antibodies and single-domain antibodiesSemantic proximity Read ↗

AI-Guided Precision in Antibody Humanization: Structural Modeling to Minimize Immunogenicity and Preserve EfficacySemantic proximity Read ↗

Biochemical Patterns of Antibody Polyreactivity Revealed Through a Bioinformatics-Based Analysis of CDR LoopsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.