Article
Immunodominance and tumor escape.
Seminars in cancer biology - 1 Feb 2002
Schreiber H, Wu T H, Nachman J, Kast W M
Abstract excerpt
Cancers in mouse and man express multiple tumor-specific as well as tumor-associated antigens. Immunodominance in the host response to these antigens can result in successive selection of heritable antigen loss variants. Immunodominance may also prevent the development of responses to new tumor-specific antigens that may arise during tumor progression. Some tumor-specific antigens are retained during tumor...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.