Article
Molecular mapping of the mouse ob mutation.
Genomics - 1 Dec 1991
Friedman J M, Leibel R L, Siegel D S, Walsh J, Bahary N
Abstract excerpt
The mouse ob mutation has been mapped relative to a series of RFLPs among the progeny of three separate mouse crosses: an intraspecific backcross, an intraspecific intercross, and an interspecific intercross. Genotypic assignment at the ob locus was made by making use of measurements of body mass index and the plasma concentrations of glucose and insulin. These data have suggested that the development of diabetes...
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