Molecular mapping of the mouse ob mutation.

doi:10.1016/0888-7543(91)90032-a

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Article

Molecular mapping of the mouse ob mutation.

Genomics - 1 Dec 1991

Friedman J M, Leibel R L, Siegel D S, Walsh J, Bahary N

Abstract excerpt

The mouse ob mutation has been mapped relative to a series of RFLPs among the progeny of three separate mouse crosses: an intraspecific backcross, an intraspecific intercross, and an interspecific intercross. Genotypic assignment at the ob locus was made by making use of measurements of body mass...

Topics

Animals
Blotting, Southern
Chromosome Mapping
Crosses, Genetic
Female
Genotype
Male
Mice
Mice, Inbred C57BL
Mice, Inbred DBA
Mice, Mutant Strains
Mutation
Obesity
Pedigree
Phenotype
Polymorphism, Restriction Fragment Length

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