Article
Identification of four chromosomal loci determining obesity in a multifactorial mouse model.
The Journal of clinical investigation - 1 Apr 1995
Warden C H, Fisler J S, Shoemaker S M, Wen P Z, Svenson K L, Pace M J, Lusis A J
Abstract excerpt
We previously described a new mouse model for multigenic obesity, designated BSB. We now report the use of a complete linkage map approach to identify loci contributing to body fat and other traits associated with obesity in this model. Four loci exhibiting linkage with body fat, or with the weig...
Topics
- Adipose Tissue
- Animals
- Body Constitution
- Causality
- Cholesterol
- Chromosome Mapping
- Crosses, Genetic
- Disease Models, Animal
- Female
- Genetic Linkage
- Genotype
- Lipoproteins
- Lod Score
- Male
- Mice
- Mice, Inbred C57BL
- Muridae
- Obesity