Article
Variation in CAPN10 in relation to type 2 diabetes, obesity and quantitative metabolic traits: studies in 6018 whites.
Molecular genetics and metabolism - 1 Dec 2006
Jensen Dorit P, Urhammer Søren A, Eiberg Hans, Borch-Johnsen Knut, Jørgensen Torben, Hansen Torben, Pedersen Oluf
Abstract excerpt
The first type 2 diabetes (T2D) gene to be identified in a genome wide scan followed by positional cloning was CAPN10 encoding the cysteine protease calpain-10. Subsequently, a large number of studies have investigated variation in CAPN10 in relation to T2D. Two CAPN10 single nucleotide polymorphisms (SNPs), the SNP43 (rs3792267) and the SNP44 (rs2975760), have been associated with T2D in some, but not all...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
