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Article

Are variants in the CAPN10 gene related to risk of type 2 diabetes? A quantitative assessment of population and family-based association studies.

American journal of human genetics - 1 Feb 2004

Song Yiqing, Niu Tianhua, Manson JoAnn E, Kwiatkowski David J, Liu Simin

Abstract excerpt

The calpain-10 gene (CAPN10) on chromosome 2q37.3 was the first candidate gene for type 2 diabetes (T2D) identified through a genomewide screen and positional cloning. One polymorphism (UCSNP-43: G-->A) and a specific haplotype combination defined by three polymorphisms (UCSNP-43, -19, and -63) w...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 14730479
DOI: 10.1086/381400
PMCID: PMC1181919

Genes

CAPN10

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14730479-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Are variants in the CAPN10 gene related to risk of type 2 diabetes? A quantitative assessment of population and family-based association studies.PMID 14730479Read ↗

Association of the calpain-10 gene with type 2 diabetes in Europeans: results of pooled and meta-analyses.Semantic proximity Read ↗

Variation in CAPN10 in relation to type 2 diabetes, obesity and quantitative metabolic traits: studies in 6018 whites.Semantic proximity Read ↗

Role of calpain-10 gene variants in familial type 2 diabetes in Caucasians.Semantic proximity Read ↗

Type 2 diabetes candidate gene CAPN10: first, but not last.Semantic proximity Read ↗

Co-existence of risk and protective haplotypes of Calpain 10 gene to type 2 diabetes in the eastern Indian population.Semantic proximity Read ↗

Calpain 10 and type 2 diabetes: are we getting closer to an explanation?Semantic proximity Read ↗

Haplotype association of calpain 10 gene variants with type 2 diabetes mellitus in an Irish sample.Semantic proximity Read ↗

Studies of association between the gene for calpain-10 and type 2 diabetes mellitus in the United Kingdom.Semantic proximity Read ↗

CAPN10 SNP43 G>A gene polymorphism and type 2 diabetes mellitus in the Asian population: a meta-analysis of 9353 participants.Semantic proximity Read ↗

Association of calpain-10 polymorphisms with type 2 diabetes in the Tunisian population.Semantic proximity Read ↗

Common polymorphisms of calpain-10 and the risk of Type 2 Diabetes in a Tunisian Arab population: a case-control study.Semantic proximity Read ↗

Type 2 diabetes and three calpain-10 gene polymorphisms in Samoans: no evidence of association.Semantic proximity Read ↗

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