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Article

Variants in the calpain-10 gene predispose to insulin resistance and elevated free fatty acid levels.

Diabetes - 1 Aug 2002

Orho-Melander Marju, Klannemark Mia, Svensson Malin K, Ridderstråle Martin, Lindgren Cecilia M, Groop Leif

Abstract excerpt

The calpain-10 gene (CAPN10) has been associated with type 2 diabetes, but information on molecular and physiological mechanisms explaining this association is limited. Here we addressed this question by studying the role of CAPN10 for phenotypes associated with type 2 diabetes and free fatty acid (FFA) metabolism. Among 395 type 2 diabetic patients and 298 nondiabetic control subjects from Finland, the SNP-43...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12145185
DOI: 10.2337/diabetes.51.8.2658

Genes

CAPN10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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